 |
|
|
 |
| |
|
|
High folate intake is associated with lower breast cancer incidence in postmenopausal women in the Malmo Diet and Cancer cohort. |
 |
 |
| |
BACKGROUND: Epidemiologic studies of associations between folate intake and breast cancer are inconclusive, but folate and other plant food nutrients appear protective in women at elevated risk. OBJECTIVE: The objective was to examine the association between folate intake and the incidence of postmenopausal breast cancer. DESIGN: This prospective study included all women aged >/=50 y (n = 11699) from the Malmö Diet and Cancer cohort. The mean follow-up time was 9.5 y. We used a modified diet-history method to collect nutrient intake data. At the end of follow-up, 392 incident invasive breast cancer cases were verified. We used proportional hazard regression to calculate hazard ratios (HRs). RESULTS: Compared with the lowest quintile, the incidence of invasive breast cancer was reduced in the highest quintile of dietary folate intake (HR: 0.56; 95% CI: 0.35, 0.90; P for trend = 0.02); total folate intake, including supplements (HR: 0.56; 95% CI: 0.34, 0.91; P for trend = 0.006); and dietary folate equivalents (HR: 0.59; 95% CI: 0.36, 0.97; P for trend = 0.01). CONCLUSION: A high folate intake was associated with a lower incidence of postmenopausal breast cancer in this cohort.
|
| |
|
|
| Type |
Journal - Bibliographic Record |
Resource Type
(If applicable)
|
|
| Author(s) |
Ericson U, Sonestedt E, Gullberg B, Olsson H, Wirfalt E. |
| Book Publisher |
|
| Journal Publisher |
Am J Clin Nutr |
| Year |
2007 |
| Pages |
434 |
| Article Title |
|
| Edition |
86 |
Contact Information
(If applicable)
|
|
Comments
(If applicable)
|
|
| |
 |
|
|
|
|
|
National Resource Center on Nutrition, Physical Activity & Aging | Florida International University, OE 200, Miami, FL 33199
Phone: 305-348-1517 | Fax: 305-348-1518 | E-mail: nutrionandaging@fiu.edu
|
|
|
